Epilepsie associée aux gliomes infiltrants de l’adulte

, par  Johan Pallud , popularité : 32%


1. Afra D, Osztie E, Sipos L, Vitanovics D (1999) Preoperative history and postoperative survival of supratentorial low-grade astrocytomas. Br J of Neurosurgery 13(3):299–305

2. Algharabil J, Kintner DB, Wang Q, Begum G, Clark PA, Yang S-S, et al.(2012) Inhibition of Na-K(+)-2Cl(-) Cotransporter isoform 1 Accelerates Temozolomidemediated Apoptosis in Glioblastoma Cancer Cells.Cell Physiol Biochem 30(1):33–48

3. Armstrong TS, Choi S, Walker J, Gilbert MR (2010) Seizure risk in brain tumor patients with conversion to generic levetiracetam. J Neurooncol 98(1):137–141

4. Aronica E, Gorter JA, Jansen GH, van Veelen CWM, van Rijen PC, Leenstra S, et al.(2003) Expression and cellular distribution of multidrug transporter proteins in two major causes of medically intractable epilepsy : focal cortical dysplasia and glioneuronal tumors.Neuroscience 118(2):417–429

5. Bauer R, Dobesberger J, Unterhofer C, Unterberger I, Walser G, Bauer G, et al. (2007) Outcome of adult patients with temporal lobe tumours and medically refractory focal epilepsy. Acta Neurochir (Wien) 149(12):1211–6– discussion 1216–7

6. Bauman G, Fisher B, Watling C, Cairncross J, Macdonald D (2009) Adult Supratentorial Low-Grade Glioma : Long-Term Experience at a Single Institution.Int J Radiat Oncol Biol Phys. doi : 10.1016/j.ijrobp.2009.01.010

7. Baumert BG, Brada M, Bernier J, Kortmann RD, Dehing-Oberije C, Collette L, et al.(2008) EORTC 22972–26991/MRC BR10 trial : Fractionated stereotactic boost following conventional radiotherapy of high gradegliomas. Radiotherapy and Oncology 88(2):163–172

8. Bähr O, Hermisson M, Rona S (2011) Intravenous and oral levetiracetam in patients with a suspected primary brain tumor and symptomatic seizures undergoing neurosurgery : the HELLO trial. Acta Neurochir (Wien) 154(2):229–235

9. Bechtereva N, Vvedenskaia, I, Dubikaitis Y, Stepanova T, Ovnatanov B, Usov V (1963) Localization of focal brain lesions by electroencephalography.Electroencephalogr Clin Neurophysiol 15:177–196

10. Berendsen S, Broekman M, Seute T,Snijders T, van Es C, de Vos F, et al.(2012) Valproic acid for the treatment of malignant gliomas : review of the preclinical rationale and published clinical results. Expert Opin Investig Drugs 21(9):1391–1415

11. Berger MS, Ghatan S, Haglund MM, DobbinsJ, Ojemann GA (1993) Low-grade gliomas associated with intractable epilepsy : seizure outcome utilizing electrocorticography during tumor resection. Journal of Neurosurgery 79(1):62–69

12. Bianchi MG, Franchi-Gazzola R, Reia L, Allegri M, Uggeri J, Chiu M,et al. (2012) Valproic acid induces the glutamate transporter excitatory amino acid transporter-3 in human oligodendroglioma cells. Neuroscience 227:260–270

13. Blecic S, Rynkowski M, De Witte O, Lefranc F (2013) Glutamate and malignant gliomas, from epilepsia to biological aggressiveness : therapeutic implications. Bulletin du cancer. doi : 10.1684/bdc.2013.1781

14. Blonski M, Pallud J, Gozé C (2013) Neoadjuvant chemotherapy may optimize the extent of resection of World Health Organization grade II gliomas:a case series of 17 patients. J Neurooncol 113(2):267–275

15. Bobustuc GC, Baker CH, Limaye A, Jenkins WD, Pearl G, Avgeropoulos NG, et al.(2010) Levetiracetam enhances p53-mediated MGMT inhibition and sensitizes glioblastoma cells to temozolomide.Neuro-Oncology 12(9):917–927

16. Bourg V, Lebrun C, Chichmanian RM, Thomas P, Frenay M (2001) Nitroso-urea-cisplatin-based chemotherapy associated with valproate : increase of haematologic toxicity. Ann Oncol 12(2):217–219

17. Brada M, Viviers L, Abson C (2003) Phase II study of primary temozolomide chemotherapy in patients with WHO grade II gliomas. Ann Oncol 14(12):1715–1721

18. Breemen MSM, Rijsman RM, Taphoorn MJB, Walchenbach R, Zwinkels H, Vecht CJ (2009) Efficacy of anti-epileptic drugs in patients with gliomas and seizures. J Neurol 256(9):1519–1526

19. Brem H, Piantadosi S, Burger PC, Walker M, Selker R, Vick NA, et al.(1995) Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy forrecurrent gliomas.The Polymer-brain Tumor Treatment Group. Lancet 345(8956):1008–1012

20. Britton JW, Cascino GD, Sharbrough FW, Kelly PJ (1994) Low-grade glial neoplasms and intractable partial epilepsy : efficacy of surgical treatment. Epilepsia 35(6):1130–1135

21. Brodie MJ, Perucca E, Ryvlin P, Ben-Menachem E, Meencke H-J, Levetiracetam Monotherapy Study Group (2007) Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Neurology 68(6):402–408

22. Brogna C, GilRobles S, Duffau H (2008) Brain tumors and epilepsy. Expert review of neurotherapeutics 8(6):941–955

23. Büttner A, Heimpel M, Eisenmenger W (1999) Sudden natural death “at the wheel” : a retrospective study over a 15-year time period (1982-1996). ForensicSci Int 103(2):101–112

24. Calatozzolo C, Gelati M, Ciusani E (2005) Expression of drug resistance proteins Pgp, MRP1, MRP3, MRP5 and GST-pi in human glioma. J Neurooncol 74(2):113–121

25. Chaichana KL, Mcgirt MJ, Laterra J, Olivi A, Quiñones-Hinojosa A (2010) Recurrence and malignant degeneration after resection of adult hemispheric low-grade gliomas. Journal of Neurosurgery 112(1):10–17

26. Chaichana KL, Parker SL, Olivi A, Quiñones-Hinojosa A (2009) Long-term seizure outcomes in adult patients undergoingprimary resection of malignant brain astrocytomas. Clinical article. Journal of Neurosurgery 111(2):282–292

27. Chalifoux R, Elisevich K (1996) Effect of ionizing radiation on partial seizures attributable to malignant cerebral tumors. Stereotact Funct Neurosurg 67(3-4):169–182

28. Chang EF, Potts MB, Keles GE, Lamborn KR, Chang SM, Barbaro NM, et al.(2008) Seizure characteristics and control following resection in 332 patients with low-grade gliomas.Journal of Neurosurgery 108(2):227–235

29. Chang EF, Smith JS, Chang SM, Lamborn KR, Prados MD, Butowski N, et al.(2008) Preoperative prognostic classification system for hemispheric low-grade gliomas in adults.Journal of Neurosurgery 109(5):817–824

30. Chavez-Blanco A, Perez-Plasencia C, Perez-Cardenas E (2006) Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines. Cancer Cell Int 6:2

31. Daly D, Thomas J (1958) Sequential alterations in the electroencephalograms of patients with brain tumors. Electroencephalogr Clin Neurophysiol 10(3):395–404

32. Danfors T, Ribom D, Berntsson SG, Smits A (2009) Epileptic seizures and survival in early disease of grade 2 gliomas.Eur J Neurol 16(7):823–831

33. Daumas-Duport C, Tucker M-L,Kolles H, Cervera P, Beuvon F, Varlet P, et al.(1997) Oligodendrogliomas. Part II : A new grading system based on morphological and imaging criteria. J Neurooncol 34(1):61–78

34. Daumas-Duport C, Varlet P, Tucker M-L, Beuvon F, Cervera P, Chodkiewicz JP (1997) Oligodendrogliomas. Part I : Patterns of growth, histological diagnosis, clinical and imaging correlations : a study of 153 cases. J Neurooncol 34(1):37–59

35. De Groot J, Sontheimer H (2011) Glutamate and the biology of gliomas. Glia 59(8):1181–1189

36. de Groot M, Reijneveld JC, Aronica E, Heimans JJ (2012) Epilepsy in patients with a brain tumour : focal epilepsy requires focused treatment. Brain 135(Pt 4):1002–1016

37. Douw L, Klein M, Fagel SS (2009) Cognitive and radiological effects of radiotherapyin patients with low-grade glioma : long-term follow-up. Lancet neurology 8(9):810–818

38. Douw L, van Dellen E, de Groot M, Heimans JJ, Klein M, Stam CJ, Reijneveld JC (2010) Epilepsy is related to theta band brain connectivity and network topology in brain tumor patients. BMC Neurosci 11:103

39. Duffau H (2012) A new concept of diffuse (low-grade) glioma surgery. Adv Tech Stand Neurosurg 38:3–27

40. Duffau H (2009) A personal consecutive series of surgically treated 51 cases of insular WHO Grade II glioma : advances and limitations. Journal of Neurosurgery 110(4):696–708

41. Duffau H, Capelle L (2004) Preferential brain locations of low-grade gliomas. Cancer 100(12):2622–2626

42. Engelhorn TT, Savaskan NEN, Schwarz MAM (2009) Cellular characterization of the peritumoral edema zone in malignant brain tumors. Cancer Sci 100(10):1856–1862

43.Englot DJ, Berger MS, Barbaro NM, Chang EF (2011) Predictors of seizure freedom after resection of supratentorial low-grade gliomas. A review. Journal of Neurosurgery 115(2):240–244

44. Englot DJ, Berger MS, Chang EF, Garcia PA (2012) Characteristics and Treatment of Seizures in Patients with High-Grade Glioma : A Review. Neurosurg Clin N Am 23(2):227–235

45. Englot DJ, Han SJ, Berger MS, Barbaro NM, Chang EF (2011) Extent of surgical resection predicts seizure freedom in low-grade temporal lobe brain tumors. Neurosurgery. doi : 10.1227/NEU.0b013e31823c3a30

46. Eyal S, Yagen B, Sobol E, Altschuler Y, Shmuel M, Bialer M (2004) The activity of antiepileptic drugs as histone deacetylase inhibitors. Epilepsia 45(7):737–744

47. Fisher RS, van Emde Boas W, Blume W, Elger C, Genton P, Lee P, Engel J (2005) Epileptic seizures and epilepsy : definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia 46(4):470–472

48. Frenay MP, Fontaine D, Vandenbos F, Lebrun C (2005) First-line nitrosourea-based chemotherapy in symptomatic non-resectable supratentorial pure low-grade astrocytomas. Eur J Neurol 12(9):685–690

49. Fu J, Shao C-J, Chen F-R, Ng H-K, Chen Z-P (2010) Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines. Neuro-Oncology 12(4):328–340

50. Gaffield ME, Culwell KR, Lee CR (2011) The use of hormonal contraception among womentaking anticonvulsant therapy. Contraception 83(1):16–29

51. Gastaut JLJ, Michel BB, Hassan SSS, Cerda MM, Bianchi LL, Gastaut HH (1979) Electroencephalography in brain edema (127 cases of brain tumor investigated by cranial computerized tomography). Electroencephalogr Clin Neurophysiol 46(3):239–255

52. Ghareeb F, Duffau H (2012) Intractable epilepsy in paralimbic Word Health Organization Grade II gliomas : should the hippocampus be resected when not invaded by the tumor ? J Neurosurg 116(6):1226–1234

53. Gilbar PJ, Brodribb TR (2001) Phenytoin and fluorouracil interaction. Ann Pharmacother 35(11):1367–1370

54. Glantz MJ, Cole BF, Forsyth PA, Recht LD, Wen PY, Chamberlain MC, et al. (2000) Practice parameter : Anticonvulsant prophylaxis in patients with newlydiagnosed brain tumors Report of the Quality Standards Subcommittee of the American Academy of Neurology.Neurology 54(10):1886–1893

55. Glauser T, Ben-Menachem E, Bourgeois B, Cnaan A, Chadwick D, Guerreiro C, et al.(2006) ILAE treatment guidelines : evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia 47(7):1094–1120

56. Gonzalez D, Elvidge A (1962) On the occurrence of epilepsy caused by astrocytoma of the cerebral hemispheres. Journal of Neurosurgery 19:470–482

57. Grezes-Rueff C, Lairy-Bounes G (1950) (E.E.G. localization of frontal tumors). Rev Neurol (Paris) 82(6):536–540

58. Grossman SA, Hochberg F, Fisher J, Chen TL, Kim L, Gregory R, et al.(1998) Increased9-aminocamptothecin dose requirements in patients on anticonvulsants.NABTT CNS Consortium. The New Approaches to Brain Tumor Therapy. Cancer Chemother Pharmacol 42(2):118–126

59. Guo H, Lai L, Butchbach MER, Lin C-LG (2002) Human glioma cells and undifferentiated primary astrocytes that express aberrant EAAT2 mRNA inhibit normal EAAT2 protein expression and prevent cell death. Mol Cell Neurosci 21(4):546–560

60. Guthrie GD, Eljamel S (2012) Impact of particular antiepileptic drugs on the survival of patients with glioblastoma multiforme. Journal of Neurosurgery 1–7

61. Hamilton W, Kernick D (2007) Clinical features of primary brain tumours : a case-control study using electronic primary care records. Br J Gen Pract 57(542):695–699

62. Harden C, Pennell P, Koppel B (2009) Practice Parameter update : Management issues for women with epilepsy—focus on pregnancy (an evidence-based review) : Vitamin K, folic acid, blood levels, and breastfeeding. Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society. Neurology. doi : 10.1212/WNL.0b013e3181a6b325

63. Hasagawa K, Aird R (1963) An EEG study of deep-seated cerebral and subtentorial lesions in comparison withcortical lesions. Electroencephalogr Clin Neurophysiol 15:934–946

64. Hefti M, Albert I, Luginbuehl V (2012) Phenytoin reduces 5-aminolevulinic acid-induced protoporphyrin IX accumulation in malignant glioma cells. J Neurooncol 108(3):443–450

65. Hegi ME,Diserens A-C, Gorlia T (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352(10):997–1003

66. Hildebrand J, Lecaille C, Perennes J, Delattre J-Y (2005) Epileptic seizures during follow-up of patients treated for primarybrain tumors. Neurology 65(2):212–215

67. Huang L, You G, Jiang T, Li G, Li S, Wang Z (2011) Correlation between tumor-related seizures and molecular genetic profile in 103 Chinese patients with low-grade gliomas : a preliminary study. Journal of the Neurological Sciences 302(1-2):63–67

68. Huberfeld G, Wittner L, Clemenceau S, Baulac M, Kaila K, Miles R, Rivera C (2007) Perturbed chloride homeostasis and GABAergic signaling in human temporal lobe epilepsy. J Neurosci 27(37):9866–9873

69. Hwang SL, Lieu AS,Kuo TH, Lin CL, Chang CZ, Huang TY, et al. (2001) Preoperative and postoperative seizures in patients with astrocytic tumours : analysis of incidence and influencing factors. J Clin Neurosci 8(5):426–429

70. Hwang S-L, Lin C-L, Lee K-S (2004) Factors influencing seizures in adult patients with supratentorial astrocytic tumors. Acta Neurochir (Wien) 146(6):589–94 : discussion 594

71. Jaeckle KA, Ballman K, Furth A, Buckner JC (2009) Correlation of enzyme-inducing anticonvulsant use with outcome of patients with glioblastoma. Neurology 73(15):1207–1213

72. Karim ABA, Maat BB, Hatlevoll RR (1996) A randomized trial on dose-response in radiation therapy of low-grade cerebral glioma : European Organization for Research and Treatment of Cancer (EORTC) Study 22844. Int J Radiat Oncol Biol Phys 36(3):549–556

73. Kiebert GM, Curran D, Aaronson NK, Bolla M, Menten J, Rutten EH, et al.(1998) Quality of life after radiation therapy of cerebral low-grade gliomas of the adult : results of a randomised phase III trial on doseresponse (EORTC trial 22844).EORTC Radiotherapy Co-operative Group. Eur J Cancer 34(12):1902–1909

74. Klein M, Engelberts NHJ, van der Ploeg HM, et al (2003) Epilepsy in low-grade gliomas : the impact on cognitive function and quality of life. Ann Neurol54(4):514–520

75. Kurita MM, Nishino SS, Ohtomo KK, Rai MM, Shirakawa HH, Mashiko HH, et al.(2007) Sodium valproate at therapeutic concentrations changes Ca^2^+response accompanied with its weak inhibition of protein kinase C in human astrocytoma cells.Prog Neuropsychopharmacol Biol Psychiatry 31(3):5–5

76. Kurzwelly D, Herrlinger U, Simon M (2010) Seizures in patients with low-grade gliomas—incidence, pathogenesis, surgical management, and pharmacotherapy. Adv Tech Stand Neurosurg 35:81–111

77. Kwan P,Arzimanoglou A, Berg AT, Brodie MJ, Allen Hauser W, Mathern G, et al.(2009) Definition of drug resistant epilepsy : Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies.Epilepsia 51(6):1069–1077

78. Lebrun C,Fontaine D, Bourg V, Ramaioli A, Chanalet S, Vandenbos F, et al. (2007) Treatment of newly diagnosed symptomatic pure low‐grade oligodendrogliomas with PCV chemotherapy. Eur J Neurol 14(4):391–398

79. Lee JW, Bromfield EB, Kesari S (2008) Antiemetic properties of the antiepileptic drug levetiracetam. N Engl J Med 359(17):1853–1853

80. Lee JW, Wen PY, Hurwitz S (2010) Morphological characteristics of brain tumors causing seizures. Arch Neurol 67(3):336–342

81. Lim DA, Tarapore P, Chang E, Burt M, Chakalian L, Barbaro N, et al. (2009) Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy : a randomized phase II pilot study. J Neurooncol 93(3):349–354

82. Liubinas SV, D’Abaco GM, Moffat BM (2014) IDH1 mutation is associated with seizures and protoplasmic subtype in patients with low-grade gliomas. Epilepsia 55(9):1438–1443

83. Lote K, Stenwig AE, Skullerud K, Hirschberg H (1998) Prevalence and prognostic significance of epilepsy inpatients with gliomas. Eur J Cancer 34(1):98–102

84. Taillandier L, Duffau H (2009) Epilepsy and insular Grade II gliomas : an interdisciplinary point of view from a retrospective monocentric series of 46 cases. http://dxdoiorg/103171/20096FOCUS09102 27(2):E8

85. Lynam LM, Lyons MK, Drazkowski JF, Sirven JI, Noe KH, Zimmerman RS, et al.(2007) Frequency of seizures in patients with newly diagnosed brain tumors : A retrospective review.Clinical neurology and neurosurgery 109(7):634–638

86. Marson AG, Al-Kharusi AM, Alwaidh M (2007) The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy : an unblinded randomised controlled trial. The Lancet 369(9566):1000–1015

87. Martino J, Taillandier L, Moritz-Gasser S, Gatignol P, Duffau H (2009) Re-operation is a safe and effective therapeutic strategy in recurrent WHO grade II gliomas within eloquent areas. Acta Neurochir (Wien) 151(5):427–36 ; discussion 436

88. Maschio M, Dinapoli L, Sperati F, Pace A, Fabi A, Vidiri A, et al. (2011) Levetiracetam monotherapy in patients with brain tumor-related epilepsy : seizure control, safety, and quality of life.J Neurooncol 104(1):205–214

89. Maschio M, Dinapoli L, Vidiri A, Pace A, Fabi A, Pompili A,et al.(2009) The role side effects play in the choice of antiepileptic therapy in brain tumor-related epilepsy : a comparative study on traditional antiepileptic drugs versus oxcarbazepine. J Exp Clin Cancer Res 28(1):60

90. Mauro AM, Bomprezzi C, MorresiS, Provinciali L, Formica F, Iacoangeli M, et al. (2007) Prevention of early postoperative seizures in patients with primary brain tumors : preliminary experience with oxcarbazepine. J Neurooncol 81(3):279–285

91. Merrell RT, Anderson SK, Meyer FB, LachanceDH (2010) Seizures in patients with glioma treated with phenytoin and levetiracetam. Journal of Neurosurgery 113(6):1176–1181

92. Milligan TA, Hurwitz S, Bromfield EB (2008) Efficacy and tolerability of levetiracetam versus phenytoin after supratentorialneurosurgery. Neurology 71(9):665–669

93. Mirsattari SM, Chong JJR, Hammond RR, Megyesi JF, Macdonald DR, Lee DH, et al.(2011) Do epileptic seizures predict outcome in patients with oligodendroglioma ?Epilepsy Research 94(1-2):39–44

94. Motamedi G, MeadorK (2003) Epilepsy and cognition. Epilepsy & behavior : E&B 4 Suppl 2:S25–38

95. Mulligan L, Ryan E, O’Brien M (2014) Genetic features of oligodendrogliomas and presence of seizures. The relationship of seizures and genetics in LGOs. Clin Neuropathol 33(4):292–298

96. Munari C, Musolino A, Daumas-Duport C, Missir O, Brunet P, Giallonardo AT, et al. (1985) Correlation between Stereo-EEG, CT-Scan and Stereotactic Biopsy Data in Epileptic Patients with Low-Grade Gliomas. Appl Neurophysiol 48(1-6):448–453

97. Nakada M, Furuta T, Hayashi Y, Minamoto T, Hamada J-I (2012) The strategy for enhancing temozolomide against malignant glioma. Front Oncol 2:98

98. Nataf F, Koziak M, Ricci A-C (2005) (Results of the Sainte-Anne - Lyons series of 318 oligodendroglioma in adults). Neuro-Chirurgie 51(3-4 Pt 2):329–351

99. Neef C, de Voogd-van der Straaten I (1988) An interaction between cytostatic and anticonvulsant drugs. Clin Pharmacol Ther 43(4):372–375

100. Neligan A, Shorvon SD (2010) Frequency and prognosis of convulsivestatus epilepticus of different causes : a systematic review. Arch Neurol 67(8):931–940

101. Ngo L, Nei M, Glass J (2006) Temozolomide treatment of refractory epilepsy in a patient with an oligodendroglioma. Epilepsia 47(7):1237–1238

102. Nishi N, Kawai S,Yonezawa T, Fujimoto K, Masui K (2009) Early appearance of high grade glioma on magnetic resonance imaging. Neurol Med Chir (Tokyo) 49(1):8–12

103. Novy J, Stupp R, Rossetti AO (2009) Pregabalin in patients with primary brain tumors and seizures : a preliminary observation. Clinical neurology and neurosurgery 111(2):171–173

104. Oberndorfer S, Piribauer M, Marosi C, Lahrmann H, Hitzenberger P, Grisold W (2005) P450 enzyme inducing and non-enzyme inducing antiepileptics in glioblastoma patients treated withstandard chemotherapy.J Neurooncol 72(3):255–260

105. Pace A, Vidiri A, Galiè E, Carosi M, Telera S, Cianciulli AM, et al.(2003) Temozolomide chemotherapy for progressive low-grade glioma : clinical benefits and radiological response.Ann Oncol 14(12):1722–1726

106. Pace A, Villani V, Di Lorenzo C, Guariglia L, Maschio M, Pompili A, et al.(2012) Epilepsy in the end-of-life phase in patients with high-grade gliomas. J Neurooncol 111(1):83–86

107. Pallud J, Devaux B, Depaulis A (2008) (Changes inspontaneous epileptic activity after selective intrahippocampal transection in a model of chronic mesial temporal lobe epilepsy).Neuro-Chirurgie 54(3):135–140

108. Pallud J, Audureau E, Blonski M (2014) Epileptic seizures in diffuse low-grade gliomas in adults. Brain 137(Pt 2):449–462

109. Pallud J, Duffau H, Razak RA, Barbarino-Monnier P, Capelle L, Fontaine D, et al.(2009) Influence of pregnancy in the behavior of diffuse gliomas : clinical cases of a French glioma study group. J Neurol 256(12):2014–2020

110. Pallud J, Le Van Quyen M, Bielle F (2014) Cortical GABAergic excitation contributes to epileptic activities around human glioma. Science Translational Medicine 6(244):244ra89–244ra89

111. Pallud J, Llitjos J-F, Dhermain F (2012) Dynamic imaging response following radiation therapy predicts long-term outcomes for diffuse low-grade gliomas. Neuro-Oncology 14(4):496–505

112. Pallud J, Mandonnet E, Deroulers C (2010) Pregnancy increases the growth rates of World Health Organization grade II gliomas.Ann Neurol 67(3):398–404

113. Pecker J, Scarabin JM, Brucher JM (1979). Démarche stéréotaxique en neurochirurgie.

114. Perry JR, Sawka C (1996) Add-on gabapentin for refractory seizures in patients with brain tumours. Can J Neurol Sci 23(2):128–131

115. Petit-Dutaillis D, Fischgold H, Houdart R, Bounes-Lairy G (1950) (Electrocorticography (ECG) in 5 cases of cerebral tumor). Rev Neurol (Paris) 82(6):501–507

116. Piepmeier J, Christopher S, Spencer D, Byrne T, Kim J, Knisel JP, et al. (1996) Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas. Neurosurgery 38(5):872–8– discussion 878–9

117. Preusser M (2011) Current concepts and management of glioblastomas.Ann Neurol 1–45

118. Puppa Della A, Denaro L, Rossetto M, Ciccarino P, Manara R, Lombardi G, et al.(2011) Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience. J Neurooncol 105(2):275–280

119. Riva M (2005) Brain tumoral epilepsy : a review. Neurol Sci 26Suppl 1:S40–2

120. Riva M, Salmaggi A, Marchioni E, Silvani A, Tomei G, Lorusso L, et al.(2006) Tumour-associated epilepsy : clinical impact and the role of referring centres in a cohort of glioblastoma patients. A multicentre study from the Lombardia Neurooncology Group. Neurol Sci 27(5):345–351

121. Rosati A, Buttolo L, Stefini R, Todeschini A, Cenzato M, Padovani A (2010) Efficacy and safety of levetiracetam in patients with glioma : a clinical prospective study. Arch Neurol 67(3):343–346

122. Rosati A,Tomassini A, Pollo B, Ambrosi C, Schwarz A, Padovani A, et al. (2009) Epilepsy in cerebral glioma : timing of appearance and histological correlations. J Neurooncol 93(3):395–400

123. Rossi GF, Scerrati M, Roselli R (1985) Epileptogenic cerebral low-grade tumors : effect of interstitial stereotactic irradiation on seizures. Appl Neurophysiol 48(1-6):127–132

124. Rossi R, Figus A, Corraine S (2010) Early presentation of de novo high grade glioma with epileptic seizures : electroclinical and neuroimaging findings. Seizure : European Journal of Epilepsy 19(8):470–474

125. Ruda R, Bello L, Duffau H, Soffietti R (2012) Seizures in low-grade gliomas : natural history, pathogenesis, and outcome after treatments.Neuro-Oncology 14(suppl 4):iv55–iv64

126. Ruda R, MagliolaU, Bertero L, Trevisan E, Bosa C, Mantovani C, et al.(2013) Seizure control following radiotherapy in patients with diffuse gliomas : a retrospective study. Neuro-Oncology 15(12):1739–1749

127. Sabel M, Giese A (2008) Safety profile of carmustine wafers in malignant glioma : a review of controlled trials and a decade of clinical experience. Curr Med Res Opin 24(11):3239–3257

128. Saria MG, Corle C, Hu J (2013) Retrospective analysis of the tolerability and activity of lacosamide in patients with brain tumors. Journal of Neurosurgery 1–5

129. Schucht P, Duffau H (2011) New-onset epilepsy : considerations for initial and follow-up MRI to detect brain tumor. Expert review of neurotherapeutics 11(8):1107–1110

130. Schucht P, Ghareeb F, Duffau H (2013) Surgery forlow-grade glioma infiltrating the central cerebral region : location as a predictive factor for neurological deficit, epileptological outcome, and quality of life. J Neurosurg 119(2):318–323

131. Schwartzbaum J, Jonsson F, Ahlbom A, Preston-Martin S, Malmer B, Lönn S, et al. (2005) Prior hospitalization for epilepsy, diabetes, and stroke and subsequent glioma and meningioma risk. Cancer Epidemiol Biomarkers Prev 14(3):643–650

132. Shamji MF, Fric-Shamji EC, Benoit BG (2009) Brain tumors and epilepsy : pathophysiology of peritumoral changes. Neurosurg Rev 32(3):275–84 ; discussion 284–6

133. Shankar A, Rajshekhar V (2003) Radiological and clinical outcome following stereotactic biopsy and radiotherapy for low-grade insular astrocytomas. Neurol India 51(4):503–506

134. Sherman JH, Moldovan K, Yeoh HK, Starke RM, Pouratian N, Shaffrey ME, et al.(2011) Impact of temozolomide chemotherapy on seizure frequency in patients with low-grade gliomas.Journal of Neurosurgery 114(6):1617–1621

135. Simó M, Velasco R, GrausF, Verger E, Gil M, Pineda E, et al. (2012) Impact of antiepileptic drugs on thrombocytopenia in glioblastoma patients treated with standard chemoradiotherapy. J Neurooncol 108(3):451–458

136. Sirven JI, Wingerchuk DM, Drazkowski JF, Lyons MK, Zimmerman RS(2004) Seizure prophylaxis in patients with brain tumors : a meta-analysis. Mayo Clin Proc 79(12):1489–1494

137. Sizoo EM, Braam L, Postma TJ, Pasman HRW, Heimans JJ, Klein M, et al.(2010) Symptoms and problems in the end-of-life phase of high-grade glioma patients.Neuro-Oncology 12(11):1162–1166

138. Smits A, Duffau H (2011) Seizures and the Natural History of WHO grade II Gliomas : a Review. Neurosurgery 1

139. Soffietti R, Baumert BG, Bello L (2010) Guidelines on management of low-grade gliomas : reportof an EFNS-EANO* Task Force. Eur J Neurol 17(9):1124–1133

140. Stockhammer F, Misch M, Helms H-J, Lengler U, Prall F, Deimling Von A, et al.(2012) IDH1/2 mutations in WHO grade II astrocytomas associated with localization and seizure as the initial symptom.Seizure : European Journal of Epilepsy 21(3):194–197

141. Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen H-J, ALA-Glioma Study Group (2006) Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma : a randomised controlled multicentre phase III trial. Lancet Oncology 7(5):392–401

142. Stupp R, Mason WP, van den Bent MJ (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352(10):987–996

143. Tandon PN, Mahapatra AK,Khosla A (2001) Epileptic seizures in supratentorial gliomas. Neurol India 49(1):55–59

144. Taphoorn MJB (2003) Neurocognitive sequelae in the treatment of low-grade gliomas. Semin Oncol 30(6 Suppl 19):45–48

145. Usery JB, Michael LM, Sills AK, Finch CK (2010) A prospective evaluation and literature review of levetiracetam use in patients with brain tumors and seizures. J Neurooncol 99(2):251–260

146. van Breemen MSM, Wilms EB, Vecht CJ (2007) Epilepsy in patients with brain tumours : epidemiology, mechanisms, and management. Lancet neurology 6(5):421–430

147. van den Bent MJ, Afra D, de Witte O, et al (2005) Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults : the EORTC 22845 randomised trial. Lancet 366(9490):985–990

148. Vecht CJ, van Breemen M (2006) Optimizing therapy of seizures in patients with brain tumors. Neurology 67(12 Suppl 4):S10–3

149. Vecht CJ, Wilms EB (2010) Seizures in low- and high-grade gliomas : current management and future outlook. Expert Rev Anticancer Ther 10(5):663–669

150. Vecht CJ, Wagner GL, Wilms EB (2003) Interactions between antiepileptic and chemotherapeutic drugs. Lancet neurology 2(7):404–409

151. Vercueil L (2011) Brain tumor epilepsy : A reappraisal and six remaining issues to be debated. Rev Neurol (Paris). doi : 10.1016/j.neurol.2011.08.007

152. Viaccoz A, Lekoubou A, Ducray F (2012) Chemotherapy in low-grade gliomas. Current opinion in oncology 24(6):694–701

153. Warnke PC, Berlis A, Weyerbrock A, Ostertag CB (1997) Significant reduction of seizure incidence and increase of benzodiazepine receptor density after interstitial radiosurgery in low-grade gliomas. Acta Neurochir Suppl 68:90–92

154. Watkins S, Sontheimer H (2012) Unique biology of gliomas : challenges andopportunities. Trends in Neurosciences 35(9):546–556

155. Weller MM, Gorlia TT, Cairncross JGJ (2011) Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma. Neurology 77(12):1156–1164

156. Werner-Wasik M, RudolerS, Preston PE, Hauck WW, Downes BM, Leeper D, et al.(1999) Immediate side effects of stereotactic radiotherapy and radiosurgery.Int J Radiat Oncol Biol Phys 43(2):299–304

157. Westphal M, Hilt DC, Bortey E, Delavault P, Olivares R, Warnke PC, et al.(2003) A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma.Neuro-Oncology 5(2):79–88

158. Whittle IR, Beaumont A (1995) Seizures in patients with supratentorial oligodendroglial tumours. Clinicopathological features and management considerations. Acta Neurochir (Wien) 135(1-2):19–24

159. Wiener P (2003) Neuroactive steroids, relaxation, and seizure control. Int J Neurosci 113(5):631–639

160. Wilby J, Kainth A, Hawkins N (2005) Clinical effectiveness, tolerability and cost-effectiveness of newer drugs for epilepsy in adults : a systematic review and economic evaluation. Health Technol Assess 9(15):1–157– iii–iv

161. Wu AS, Trinh VT, Suki D (2013) A prospective randomized trial of perioperative seizure prophylaxis in patients with intraparenchymal brain tumors. Journal of Neurosurgery 1–11

162. Yoon HW, Giraldo EA, Wijdicks E (2011) Valproic acid and warfarin : an underrecognized drug interaction. Neurocritical care

163. You G,Sha Z-Y, Yan W (2012) Seizure characteristics and outcomes in 508 Chinese adult patients undergoing primary resection of low-grade gliomas : a clinicopathological study. Neuro-Oncology 14(2):230–241

164. Yuan Y, Xiang W, Yanhui L, Ruofei L, Shuang L, Yingjun F, et al.(2013) Ki-67 overexpression in WHO grade II gliomas is associated with poor postoperative seizure control.Seizure : European Journal of Epilepsy 1–5

165. Yuen TI, Morokoff AP, Bjorksten A (2012) Glutamate is associated with a higher risk of seizures in patients with gliomas. Neurology. doi : 10.1212/WNL.0b013e318266fa89

166. Zaatreh MM, Firlik KS, Spencer DD, Spencer SS (2003) Temporal lobe tumoral epilepsy : characteristics and predictors of surgical outcome. Neurology 61(5):636–641

167. Zhong Z, Wang Z, Wang Y, You G, Jiang T (2015) IDH1/2 mutation is associated with seizure as an initial symptom in low-grade glioma : A report of 311 Chinese adult glioma patients. Epilepsy Research 109:100–105

168. Zschocke J, Allritz C, Engele J, Rein T (2007) DNA methylation dependent silencing of the human glutamate transporter EAAT2 gene in glial cells.Glia 55(7):663–674